|
|
arachidonic_acid + O2 <=> (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
BK
|
|
BRENDA:
BR37067
KEGG:
R01596
MetaCyc:
ARACHIDONATE-12-LIPOXYGENASE-RXN
SABIO-RK:
1745
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> hepoxilin_A3
|
5.4.4
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
–
|
K
|
|
KEGG:
R07039
MetaCyc:
RXN-14948
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> hepoxilin_B3
|
5.4.4
|
–
|
K
|
|
KEGG:
R07040
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> (5Z,8Z,10E,14Z)-12-oxoicosa-5,8,10,14-tetraenoic_acid + H2O
|
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
|
–
|
|
|
MetaCyc:
RXN-14942
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> (10R)-hydroxy-(11S,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoic_acid
|
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
|
|
|
MetaCyc:
RXN-14951
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate + reduced_acceptor <=> (5Z,8Z,10E,14Z)-(12S)-12-hydroxyeicosa-5,8,10,14-tetraenoate + H2O + acceptor
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20569
|
|
|
|
2 arachidonic_acid + 2 O2 + 2 H+ <=> (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate + (5Z,8Z,10E,14Z)-(12S)-12-hydroxyeicosa-5,8,10,14-tetraenoate + H2O
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
|
|
BRENDA:
BS394703
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> 11-oxoprostatrienoic_acid
|
5.3.99.6
allene-oxide cyclase
|
–
|
|
|
BRENDA:
BS427744
|
|
|
|
arachidonic_acid + O2 <=> 15-hydroperoxyeicosatetraenoic_acid + (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
|
1.13.11.33
arachidonate 15-lipoxygenase
|
–
|
|
|
BRENDA:
BS376302
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> (10R)-hydroxy-(11S,12S)-epoxyeicosa-(5Z,8Z,14Z)-trienoic_acid + (8R)-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoic_acid + (5Z,8Z,10E,14Z)-12-oxoicosa-5,8,10,14-tetraenoic_acid
|
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
|
–
|
|
|
BRENDA:
BS429447
|
|
|
|
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate <=> (10R)-hydroxy-(11S,12S)-epoxyeicosa-(5Z,8Z,14Z)-trienoic_acid + (8R)-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoic_acid + H2O
|
4.2.1.92
hydroperoxide dehydratase
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
–
|
|
|
BRENDA:
BS363387
|
|